I have the latest SAS defs and using the free edition, some registry entries are not being cleared from the Ask.Toolbar infection. Specifically:
SAS detects these and says it removed them, but upon reboot and re-scan, they are still there. I know I am not infected with this Toolbar anymore, I think it is just because SAS is a 32bit app it can't access those 64-bit areas of the registry. What I think you need is a 64-bit "helper" app that SAS can call into play to operate on 64-bit areas of the registry in such cases.
by the way thanks for the great app!