I don't know if there is a solution to this, or a topic I'm missing, but I did do a search on the forums and I haven't seen this so here we go.
If the notification window pops up, or if I select update from the program itself when there's a program update available, I get told that I need to be running the program in an Administrative account. This occurs no matter what I do. I've tried closing the program totally, then right-clicking and running SUPERAntiSpyware as Administrator. I've tried starting it in an Administrative account. I've tried simply clicking the "Update Now" option. None of this works.
If there's a fix for this please let me know. Otherwise, my suggestion is to fix it. I don't care if you need to trigger a UAC prompt or what, but it's somewhat annoying that the program update option in the program itself will not work. Whenever an update is available, I groan because I know I'll have to download and install it manually.